Literature summary extracted from

Goesswein, T.; Kocot, A.; Emmert, G.; Kreuz, W.; Martinez-Saguer, I.; Aygoeren-Puersuen, E.; Rusicke, E.; Bork, K.; Oldenburg, J.; Mueller, C.R.
Mutational spectrum of the C1INH (SERPING1) gene in patients with hereditary angioedema (2008), Cytogenet. Genome Res., 121, 181-188.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
3.4.21.41	C1INH	sole inhibitor of the activated proteases C1r and C1s. Hereditary angioedema results from functional deficiency of the C1 inhibitor (C1INH) protein, which plays a key role in the classical pathway of complement activation	Homo sapiens

Organism

EC Number	Organism	UniProt	Comment	Textmining
3.4.21.41	Homo sapiens	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
3.4.21.41	liver	-	Homo sapiens	-

Synonyms

EC Number	Synonyms	Comment	Organism
3.4.21.41	C1r	-	Homo sapiens

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Release 2023.1 (January 2023)